Find A Professional or Spa Location | The Science

FREE STANDARD SHIPPING with $100 purchase!

Professionals Only

Works Well With:
Benefit Clean

Benefit Clean

Gentle Cleanser

More Details >



Resurfacing Treatment

More Details >

Opti Crystal

Opti Crystal

Chirally Correct Eye Serum

More Details >

Serum 16


Serum 16

Featuring LG-Retinex

Dual retinol rapid renewal complex

$78.00 USD


Containing 16% LG-Retinex—a proprietary GAG-enhanced encapsulation of retinol and retinaldehyde—Serum 16 is the closest thing to prescription-strength age defiance without a prescription. In a six-week clinical study, this breakthrough superserum by CosMedix visibly reduced the appearance of sun damage, age spots and deep lines, including crow's feet.

Clinical Results:
  • 88% reported noticeably firmer skin in two weeks
  • 75% reported less apparent wrinkles in four weeks
  • Over 90% reported brighter-looking skin in six weeks

Serum 16: Apply a pea-sized amount to clean skin as tolerated every 1-3 nights, working up to nightly use. May be followed with moisturizer if additional hydration is needed. Protect your results by wearing sunscreen daily.

Be Sun Smart. CosMedix always recommends daily use of sunscreen to protect skin against sunburn and premature aging. Common Sense Cautions: For external use only. Avoid contact with eyes. Keep out of reach of children.

Serum 16: Aqua, Hamamelis Virginiana (Witch Hazel) Water, Tocopheryl Acetate, Sodium Lactate, Glycerin, Galactoarabinan, Sodium PCA, Phospholipids, Ethylhexylglycerin, Xanthan Gum, Glycosaminoglycans, Leuconostoc/Radish Root Ferment Filtrate, Retinol, Retinal, Tetrasodium EDTA, Proline (L), Sodium Hyaluronate, Sodium Hydroxymethylglycinate, Squalane, Aniba Rosaeodora (Rosewood) Wood Oil, Lavandula Angustifolia (Lavender) Oil, Helianthus Annuus (Sunflower) Seed Oil, Cassia Angustifolia Seed Polysaccharide, Dimethicone, Sorbitol, Polysorbate 20, Potassium Sorbate

Q & A Guidelines

Tracey PinderMedia PAAge: 35-44Gender: femaleSkin Tone: LightSkin Type: Combination
06-Feb-2013Amazingly Age Defying!!
Pros:Easy to Use, Nice Finish, Performs Well, Wonderful Fragrance
Serum 16 has truly changed my skin and my life! The first thing people see is our faces... and when we look good.... we feel good!! Serum 16 is hands down the best product I have ever used that has made such a dramtic difference within few days!!! I had some sun damage and fine lines... I also had some uneven patches and some discoloration...but Serum 16 has given me a complete makeover!.. my skin has literally changed! It is smooth, clear, soft, and young looking.. fine lines have faded away!! It's unbelievable. I recommend this product to anyone that wants soft young beautiful skin!! I am amazed!! I Recommend This Product
One person liked this comment.

David V.Los AngelesAge: 35-44Gender: maleSkin Tone: Medium (pink undertones)Skin Type: Oily
27-Dec-2012Great Retinol Product for Sensitive Skin!
Pros:Easy to Use, Exfoliates Gently, Light, Nice Finish, Performs Well, Wonderful Fragrance
Within three days I noticed a complete change in the overall tone and texture of my skin. I have been using professional skin care for over 10 years and have never experienced such rapid results, the fine lines around my eyes are gone! My skin tone is even without any irritation I have had while using other Vitamin A products. A true Hero product!! I Recommend This Product

Don’t be fooled by unauthorized resellers!

Sign Up for E-Newsletter and Exclusive Offers Today!

marketing automation software