Clean. Clinical. Luxurious.
Clinically Proven Efficacy.
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Aqua/Water/Eau, Polysorbate 60, Lactic Acid (L), Isopropyl Myristate, Glyceryl Stearate, Hamamelis Virginiana (Witch Hazel) Water, Stearic Acid, Cetearyl Alcohol, Glycerin, Sodium Hydroxide, Leuconostoc/Radish Root Ferment Filtrate, Tartaric Acid (L), Retinyl Acetate, Albumen, Cetyl Alcohol, Benzyl Alcohol, Malic Acid (L), Olea Europaea (Olive) Fruit Oil, Retinol, Pichia/Resveratrol Ferment Extract, Resveratrol Dimethyl Ether, Galactoarabinan, Proline (L), Retinyl Palmitate, Citrus Grandis (Grapefruit) Peel Oil, Cananga Odorata (Ylang Ylang) Flower Oil, Bisabolol (L-Alpha), Tocopheryl Acetate (D-Alpha), Aloe Barbadensis Leaf Juice Powder, Allantoin, Daucus Carota Sativa (Carrot) Root Extract, Prunus Amygdalus Dulcis (Sweet Almond) Oil, Helianthus Annuus (Sunflower) Seed Oil, Chamomilla Recutita (Matricaria) Flower Extract, Tocopherol (D-Alpha), Althaea Officinalis (Marshmallow) Root Extract, Alcohol, Citric Acid, Polysorbate 20, Potassium Sorbate, Limonene, Sodium Gluconate, Bha, Behenyl Alcohol, Caprylhydroxamic Acid, Alcohol Denat., Bht, Xanthan Gum, Phenoxyethanol.
Apple (fruit)
Apple, rich in antioxidants and natural alpha-hydroxy acids, helps exfoliate dead skin cells and promote cell turnover for a brighter, smoother complexion. Its high vitamin C content also supports collagen production and protects the skin from environmental damage, leaving it looking refreshed and youthful.
Lightweight with a silky, fast-absorbing texture that glides smoothly onto the skin, leaving it feeling soft and refreshed without any greasy residue.
AM - We do not recommend this product for use in the morning as it may cause skin sensitivity to sun.
PM - Apply a small amount to freshly cleansed and toned skin 2-4 times weekly as part of your nightly regimen. Use as tolerated. Follow with a moisturizer if further hydration is needed.
Clean. Clinical. Luxurious.
Clinically Proven Efficacy.
This retinol treatment delivers impressive results for age-defying care. Customers said it "makes skin feel smooth and hydrated" with visible improvements in texture, tone, and pigmentation. Many report reduced fine lines, clearer pores, and a youthful glow. While gentle for most, some experienced initial dryness or sensitivity. Best used at night with sunscreen during the day.
Amazing. Love this product.
This product is game changing! After one week, I see a difference! I love Cosmetics!
This has helped my face when nothing else couldn't!
This is my second buy of this product and it helps with my dark spots , not too harsh on the skin but really does the job like an intense peel , highly recommend for bright skin the next morning and for pigmentation
Amazing product.
Wonderful product! Love the way my skin feels after
Very impressed with this product-my skin was immediately more balanced and texture was just. I have very very sensitive skin and this product worked well. Would definately buy again!
Very impressed with this product-my skin was immediately more balanced and texture was just. I have very very sensitive skin and this product worked well. Would definately buy again!
Tightens and tones. Improves texture. Just make sure to apply at night and use sunscreen during the day!
This product makes my skin very smooth and soft. I will contine to buy it even though it is a little pricy.
This product makes my skin very smooth and soft. I will contine to buy it even though it is a little pricy.
This product is awesome. I use it with Simply Brilliant and it made a difference in my pigment issues and the tone of my skin and neck. I love these products and will be adding more to my regimen.
This product has been a life changer! I suffer from adult acne and it has gotten worse over the years until I started using Cosmedix, especially the Define. My skin looks smoother and softer. My acne scars are also starting to disappear. It also lasts a long time since a little goes a long way.
This product has been a life changer! I suffer from adult acne and it has gotten worse over the years until I started using Cosmedix, especially the Define. My skin looks smoother and softer. My acne scars are also starting to disappear. It also lasts a long time since a little goes a long way.
This made a huge difference in my skin tone and overall texture!
This has now been added to my skin care routine. This product feels great to the touch and leaves my face and neck feeling moisturized and soft.
This has now been added to my skin care routine. This product feels great to the touch and leaves my face and neck feeling moisturized and soft.
Still a little early after purchasing to determine full results but so far my skin appears smoother, with fewer pigmentation patches.
Started using cosmedix after a spa visit. I love all of the products but definitely saw a big difference after using Define for a couple of weeks. It is now part of my routine 3 or 4 times a week. I love when people tell me how great my skin looks.
Started using cosmedix after a spa visit. I love all of the products but definitely saw a big difference after using Define for a couple of weeks. It is now part of my routine 3 or 4 times a week. I love when people tell me how great my skin looks.
So far this retinol has been amazing for my sensitive and acne prone skin. I've used several others.. with extreme dryness and redness. My face doesn't feel tight and raw in the morning. I can use it three times a week versus with others only once a week. I do get very small one or two acne bumps. That's normal for my skin. Even though this is gentle, I would definitely still use your sunscreen. Or don't go in the direct sun after using it. So far everything from this website has been a godsend for my poor sad skin.
omg amazing product !!!!!!
Nice product, feels great.
My skin has never looked or felt better! I use Define every other day to avoid over drying and it works like a dream!
My order arrived safe + sound....and my face is happy to have a new tube of Cosmedix to use....thanks for a great product !!!
My favorite and now ONLY face cream! Highly recommend
Love, love, love this cream! I've been using it for over a year consistently and I feel like my skin is smoother, less bumpy, my dark spots are significantly lighter. I really wish I would have taken before pictures. But I can't say enough good things about this product.
Love this product. I use in in conjunction with my refine
Love this product. I use in in conjunction with my refine
Love this product! Smooths and evens my skin with no irritation. I'm 57 and I've used this product for years and credit it with keeping my skin youthful looking.
Love Define. My skin looks absolutely glowing and youthful when I use define. It's hard to explain, but my face, neck, and declotte look so much younger than my actual age off 69. I've used Cosmedix products off and on for 10+ years and when I'm "on" with Cosmedix, I see a lovely difference. Cosmedix is now my skin care of choice. My older friends are envious of my beautiful skin. I recommend Cosmedix.
on all order over $160
within 30 days of purchase
by Aestehticians & Dermatologists
Define Age-Defying Treatment with Hydroxy Acids & Retinol
$90.00