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NEW ARRIVAL
Microbiome Renewal Complexion Set
The perfect introduction to COSMEDIX. Two professional daily essentials that gently exfoliate, replenish hydration, and help support a healthy-looking skin barrier and balanced microbiome.
Purity Clean: 5 FL OZ / 150 mL
Harmonize: NET WT 1.87 OZ / 53 g
✓ Gently exfoliates with L-Lactic Acid to help smooth texture and reveal brighter-looking skin
✓ Helps support a balanced skin microbiome for a healthier-looking complexion
✓ Replenishes hydration with adaptogenic botanicals and Snow Mushroom
✓ Supports a stronger-looking skin barrier with postbiotic-derived ingredients
✓ Two everyday essentials expertly paired for a simple, effective professional routine
Microbiome Renewal is a limited-edition holiday set featuring Purity Clean and Harmonize, two of COSMEDIX's most trusted daily essentials expertly paired to gently exfoliate, replenish hydration, and help support a healthy-looking skin barrier. Designed as the perfect introduction to professional skincare, this duo delivers a complete complexion ritual at an accessible entry price.
Purity Clean is an exfoliating cleanser formulated with 5% L-Lactic Acid to gently resurface rough, uneven texture while removing impurities. Unlike harsh scrubs that can compromise the skin barrier, this AHA-based formula dissolves dead surface cells to help reveal smoother, brighter-looking skin. It's the bestselling cleanser in the COSMEDIX line, trusted by aestheticians as a daily treatment cleanser that exfoliates and cleanses in one step.
Harmonize is a microbiome-supporting moisturizer formulated with Lactobacillus Ferment Lysate Filtrate (a postbiotic-derived ingredient), Tremella Fuciformis (Snow Mushroom), and a blend of adaptogenic botanicals including Reishi, Chaga, and Ashwagandha. This formula helps support the skin's natural microbiome balance while delivering deep, lasting hydration through Squalane and Mango Seed Butter. The result is skin that looks calmer, more balanced, and better equipped to maintain its own moisture.
Together, these two formulas create a daily ritual that addresses the fundamentals: Purity Clean resurfaces and renews, and Harmonize restores and protects. The pairing works because gentle exfoliation helps optimize how skin receives hydration, while microbiome-supporting care helps maintain the results of that renewal.
This set reflects COSMEDIX's core philosophy that professional skincare should be simple, effective, and approachable. Aestheticians recommend this exact pairing for clients beginning their professional skincare journey or anyone seeking a streamlined routine that covers cleansing, exfoliation, hydration, and barrier support in just two steps.
At $85 (a $113 value), Microbiome Renewal offers 25% savings on two professional favorites. Limited edition. Available only this holiday season.
- What is the Microbiome Renewal set?
A: Microbiome Renewal is a limited-edition holiday set pairing Purity Clean (an exfoliating cleanser with 5% L-Lactic Acid) with Harmonize (a microbiome-supporting moisturizer with postbiotic-derived Lactobacillus and adaptogenic botanicals). Together they form a complete daily cleansing and hydration ritual. - Who is Microbiome Renewal best for?
A. Anyone looking for a simple, effective professional skincare routine. It's especially ideal for those new to COSMEDIX or professional-grade skincare, those with rough or uneven texture, anyone concerned with skin barrier health, or gift-givers who want a thoughtful introduction to clinical skincare. - What does "microbiome care" mean in skincare?A. Your skin's microbiome is the community of beneficial microorganisms that live on its surface and help maintain barrier health. Harmonize contains Lactobacillus Ferment Lysate Filtrate (a postbiotic-derived ingredient) that helps support this natural ecosystem, promoting skin that looks calmer, more balanced, and better hydrated.
- Does Purity Clean contain AHA? Will it irritate my skin?
A. Yes, Purity Clean contains 5% L-Lactic Acid, a gentle AHA. It's formulated to be mild enough for twice-daily use without stripping or irritating skin. Lactic Acid is one of the gentlest AHAs because it also has hydrating properties. However, always follow with sunscreen in the morning since AHAs can increase sun sensitivity. - Can I use Purity Clean if I have sensitive skin?
A. Purity Clean is generally well-tolerated, but if you have a very reactive or compromised barrier, Elite Gentle Clean (in the Elite Balance set) may be a better starting cleanser. Purity Clean's L-Lactic Acid provides gentle exfoliation that most skin types handle well with daily use. - What are adaptogens in skincare?
A. Adaptogens are botanical ingredients traditionally used to help the body manage stress. In Harmonize, adaptogenic extracts like Reishi Mushroom, Chaga, Ashwagandha, and Rhodiola help support the appearance of calmer, more resilient-looking skin and support the skin's natural ability to maintain hydration and balance. - How is Harmonize different from a regular moisturizer?
A. Harmonize goes beyond surface hydration. Its postbiotic-derived Lactobacillus and Snow Mushroom (Tremella Fuciformis) work to help support the skin's natural microbiome and moisture barrier, meaning skin becomes better at maintaining its own hydration over time rather than just feeling moisturized temporarily. - Can I add serums between these two steps?
A. Absolutely. After cleansing with Purity Clean, apply any treatment serums (brightening, anti-aging, hydrating) and then follow with Harmonize as your final moisturizing step. This duo is designed as a foundation that pairs well with any COSMEDIX serum. - Why do aestheticians recommend this pairing?
A. Aestheticians trust Purity Clean because it's a two-in-one exfoliant and cleanser that's gentle enough for daily use. Paired with Harmonize, it creates a complete routine that covers cleansing, exfoliation, hydration, and barrier support in just two steps, making it the ideal starter ritual for new professional skincare clients. - Is this set available year-round?
A. No. Microbiome Renewal is a limited-edition holiday exclusive at this special pricing ($113 value for $85). Both Purity Clean and Harmonize are available individually year-round at full retail, but the 25% savings is only available this season.
PURITY CLEAN:
AQUA/WATER/EAU, GLYCERIN, SODIUM COCOAMPHOACETATE, LACTIC ACID, COCAMIDOPROPYL BETAINE, LAURYL GLUCOSIDE, GLYCOL DISTEARATE, COCO-GLUCOSIDE, GLYCERYL OLEATE, SODIUM COCOYL GLUTAMATE, SODIUM LAURYL GLUCOSE CARBOXYLATE, PHENOXYETHANOL, SODIUM CHLORIDE, CITRIC ACID, MELIA AZADIRACHTA LEAF EXTRACT, LAVANDULA ANGUSTIFOLIA (LAVENDER) OIL, MENTHA PIPERITA (PEPPERMINT) OIL, MELIA AZADIRACHTA FLOWER EXTRACT, CORALLINA OFFICINALIS EXTRACT, ETHYLHEXYLGLYCERIN, COCCINIA INDICA FRUIT EXTRACT, MELALEUCA ALTERNIFOLIA LEAF OIL, XANTHAN GUM, ALOE BARBADENSIS FLOWER EXTRACT, SOLANUM MELONGENA FRUIT EXTRACT, GLUCURONIC ACID, CURCUMA LONGA RIZOMA EXTRACT, OCIMUM BASILICUM FLOWER/LEAF EXTRACT, OCIMUM SANCTUM LEAF EXTRACT, RIBOFLAVIN, TOCOPHEROL, ALOE BARBADENSIS LEAF JUICE, HYDROGENATED PALM GLYCERIDES CITRATE.
HARMONIZE:
AQUA/WATER/EAU, GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, PENTYLENE GLYCOL, GLYCERYL STEARATE, HYDROGENATED ETHYLHEXYL OLIVATE, LACTOBACILLUS FERMENT LYSATE FILTRATE, SQUALANE, CETEARYL ALCOHOL, MANGIFERA INDICA (MANGO) SEED BUTTER, VITIS VINIFERA (GRAPE) FRUIT EXTRACT, ZINGIBER OFFICINALE (GINGER) ROOT EXTRACT, BOSWELLIA SERRATA EXTRACT, CHLORELLA VULGARIS EXTRACT, RHODIOLA ROSEA ROOT EXTRACT, INONOTUS OBLIQUUS (MUSHROOM) EXTRACT, GANODERMA LUCIDUM (MUSHROOM) EXTRACT, WITHANIA SOMNIFERA ROOT EXTRACT, LEUCONOSTOC/RADISH ROOT FERMENT FILTRATE, POPULUS TREMULOIDES BARK EXTRACT, TREMELLA FUCIFORMIS SPOROCARP EXTRACT, PANTHENOL (D), BISABOLOL, XANTHAN GUM, HYDROXYACETOPHENONE, AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER, SODIUM STEAROYL LACTYLATE, 1,2-HEXANEDIOL, CAPRYLYL GLYCOL, SODIUM HYDROXIDE, HYDROGENATED OLIVE OIL UNSAPONIFIABLES, PROPANEDIOL, LAVANDULA ANGUSTIFOLIA (LAVENDER) FLOWER EXTRACT, SODIUM PHYTATE, CITRIC ACID, LACTIC ACID, SODIUM BENZOATE, COUMARIN, LINALOOL.
Benefits & Usage
Botanical Ingredient
Tremella Fuciformis (Snow Mushroom Sporocarp)
Snow Mushroom holds up to 500 times its weight in water and penetrates deeper into skin than hyaluronic acid alone, helping to deliver lasting hydration and supporting a visibly plumper, more supple-looking complexion.
Product Form
The pairing is intentional: gentle resurfacing helps skin receive and retain the hydration and barrier-support benefits of Harmonize more effectively.
HOW TO APPLY
AM + PM —
Step 1: Apply Purity Clean to damp skin, massaging gently for 30 to 60 seconds. Rinse thoroughly with lukewarm water and pat dry.
Step 2: Apply one pump of Harmonize to face and neck, pressing gently into skin until absorbed.
Pro Tip: Because Purity Clean contains L-Lactic Acid, always follow your AM routine with sunscreen. This cleanser is gentle enough for twice-daily use without stripping skin.
Complexion System for Gentle Exfoliation + Microbiome Care
CLEAN & CLINICAL, BACKED BY SCIENCE
Botanical ingredients meet clinical-grade actives for proven results.
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Great product! 2nd time purchasing
As I do like other Cosmedix products, this Moisturizer was not moisturizing enough, so I am currently using the Night Creme
as my day product.
Absolutely love this moisturizer! It’s light weight but does the trick to keep my face from being dry. Highly recommend!
Love how it goes on with a subtle fragrance.
I’m an esthetician and having been using this product for 5 years now. I am in my early 50s and still have combination skin. It’s is fabulous!! Perfect amount of moisture! Feels heavenly on the skin.
I really like Harmonize. It helps with fine lines and keeps my skin looking soft and dewy.
Extremely moisturizing
This moisturizer was recommended by my esthetician and it has worked wonders on my skin! Does exactly what it says. Im already on my second bottle.
Great moisturizer and love the Cosmedix line.
Love this moisturizer; it’s very smooth and leaves my skin feeling very dewy
I have sensitive skin, and my esthetician let me try a sample of this cream. It felt lightweight, wasn't greasy at all, and worked perfectly for my skin. However, I still haven't received the full size. My first order was sent to the wrong address, and the replacement got lost during delivery
Best moisturizer, been using it for 3 years now
This is the best moisturizer I've found for combination skin. It keeps my skin hydrated without feeling greasy and helps balance both dry and oily areas. Highly recommend!
This product feels so clean going on and absorbs rather quickly into the skin. When I use itovernight I wake up to refreshed skin. I highly recommend it.
Using for a couple of years. Lightweight, hydrating and a great product
The benefits are one thing, but the smell of an effective product always is a good feeling!
Lightweight but moisturizing
Harmonize moisturizer is wonderful. It’s a light cream that I use at nighttime.
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