Peptide Rich Defense SPF 50

$64.00
Take skin defense to a whole new level with Peptide-Rich Defense: a sun-shielding, multi-tasking, age-defying moisturizer that helps to replenish moisture loss, reverse visible signs of aging and guard the skin against the sun's harmful rays. Formulated with powerhouse peptides, trehalose, amino acids, natural botanical extracts and vitamin E, this bestselling moisturizer and sunscreen brings science and nature together to help smooth the look of fine lines and wrinkles, deeply nourish the skin and help protect skin against free-radical damage. Uber-hydrating but never greasy, the lightweight formula absorbs quickly into the skin for a velvety, white cast-free finish. The result is a restored, radiant and more youthful-looking complexion.
1.7 oz. / 50 mL
Build Your Routine
  • Helps protect the skin with Broad Spectrum SPF 50 sunscreen
  • Helps smooth the look of fine lines and wrinkles
  • Deeply hydrates, soothes and nourishes the complexion

Skin contends with UV radiation, environmental pollution, and constant screen time on a daily basis, all of which quietly accelerate visible aging and compromise barrier health. Peptide-Rich Defense is a peptide moisturizer with SPF 50 built to respond to that reality; it delivers broad-spectrum protection while reinforcing the skin’s structure at the same time.

It includes a carefully selected peptide complex designed to support collagen integrity and help soften the appearance of fine lines.

Instead of approaching sunscreen as a standalone step, this formula treats protection as part of a wider skin-conditioning system. The peptides work alongside moisturizing agents to keep your skin feeling resilient throughout the day.

This is SPF 50 for all skin types, and it shields against UVA and UVB exposure, which are among the primary causes of premature aging, uneven tone, and loss of firmness. The texture is lightweight and refined, absorbing evenly without leaving a dense residue, leaving your skin hydrated.

The formula also aligns with a barrier-first philosophy, as protection alone is never enough if the skin barrier is already compromised. Peptide-Rich Defense supports moisture balance while helping reduce the visible impact of environmental stress, ideal for those experiencing sensitivity or dryness triggered by daily exposure.

Suitable for all skin types, it integrates easily into morning routines. Apply after cleansing and any treatment serums, and allow it to absorb fully before makeup. The finish layers smoothly without pilling, which makes it a reliable final step before starting the day. For continued protection, reapplication is recommended when exposed to direct sunlight for extended periods.

As a result, your skin appears more even, supported, and better able to maintain its natural clarity over time.

AM - Cleanse and tone skin. Prep skin with a daytime serum like Cell ID Nutritive Defense Serum. Liberally apply a quarter-sized amount of Peptide-Rich Defense to face, neck, décolletage and hands 15 minutes prior to exposure to the sun. Reapply at least every 2 hours. Makes the perfect prep step before makeup application.

PM - We do not recommend applying moisturizers with SPF ingredients at night.

Frequently Asked Questions (FAQs)

1. What makes Peptide-Rich Defense different from a regular sunscreen?

Most sunscreens focus only on UV protection. Peptide-Rich Defense combines SPF 50 protection with peptide technology that supports the skin’s structure. It helps address visible aging concerns while also protecting against future damage; it functions as both a moisturizer and an anti-aging sunscreen in one step.

2. Can this be used on sensitive or compromised skin?

Yes, the formula is designed to respect the skin barrier and focuses on maintaining hydration while delivering protection. This makes it suitable for skin that reacts easily or is recovering from environmental stress. As with any product, patch testing is a good first step if sensitivity is a concern.

3. Will it leave a white cast or feel heavy on the skin?

The texture is lightweight and designed to blend evenly into the skin. It absorbs without leaving a thick residue, making it comfortable for daily wear.

4. Is this suitable for all skin types?

The formula is balanced to work across oily, dry, combination, and normal skin. It hydrates without excess shine and protects without clogging or heaviness, making it a versatile daily option.

5. How should it be applied in a routine?

Apply in the morning after cleansing and treatment products. Use a moderate amount and spread evenly across the face and neck, and allow it to absorb before applying makeup. Reapply as needed during prolonged sun exposure.

6. Does this replace a regular moisturizer?

It may, as the formula provides hydration while delivering sun protection, which allows it to function as the final moisturizing step in a morning routine. Those with very dry skin may prefer layering it over a richer moisturizer.

7. What role do peptides play in this formula?

Peptides help support the firmness and smoothness of your skin by encouraging a more resilient look over time. In this formula, they complement daily sun protection by addressing visible signs of aging resulting from long-term environmental exposure.

8. How long does one bottle typically last?

With daily morning use, a bottle usually lasts around four to six weeks, depending on how much product is applied and whether it is reapplied throughout the day. A consistent amount ensures effective protection without overuse.

AM Use
Lotion
All skin types

Benefits & Usage

Transformative Ingredients

Clean. Clinical. Luxurious

Clinically Proven Efficacy

  • Instantly hydrates and soothes the skin

  • Locks in moisture for lasting hydration

  • An antioxidant that helps fight free radical damage and promote skin healing to help reduce the signs of aging

Customers praised this SPF 50 moisturizer for its lightweight, non-greasy formula that leaves no white cast and works well under makeup. Many noted it provides excellent sun protection while delivering hydration and a dewy glow. Some mentioned occasional stock issues and a few experienced skin irritation after prolonged use.

  • Love this sunscreen! Only one that has never broken my skin out. Also I love the dewy look.
  • Perfect balance of hydration, skin protection, and anti-aging benefits—all in one bottle.
  • Blends into my skin so smoothly with no grey or white cast. Keeps it soft all day.
Moisturizer (positive)Skin (positive)Texture (positive)Makeup (positive)Peptides (positive)
  • 5 stars: 192 (88%)
  • 4 stars: 20 (9%)
  • 3 stars: 5 (2%)
  • 2 stars: 0 (0%)
  • 1 star: 1 (0%)
S
Sylvia M.
Quality:
Needs improvement
Excellent quality
Value:
Not a good value
Excellent value
Professional treatments: Occasionally
Age: Above 60 years old
Gender: Female
Recommends this product: Yes
Love it! My face feels nicely hydrated without feeling oily.

Love it! My face feels nicely hydrated without feeling oily.

T
TINA M.
Quality:
Needs improvement
Excellent quality
Value:
Not a good value
Excellent value
Professional treatments: No
Age: 40 to 60 years old
Gender: Female
Recommends this product: Yes
Fantastic product! Great on my sensitive skin and very moisturizing

Fantastic product! Great on my sensitive skin and very moisturizing.

A
Anonymous
Quality:
Needs improvement
Excellent quality
Value:
Not a good value
Excellent value
Professional treatments: Occasionally
Age: 40 to 60 years old
Gender: Female
Recommends this product: Yes
My new favorite SPF

My new favorite SPF. It makes my skin so soft and glowy!

A
Alicia F.
Quality:
Needs improvement
Excellent quality
Value:
Not a good value
Excellent value
Professional treatments: Occasionally
Age: Above 60 years old
Gender: Female
Recommends this product: Yes
Does the job

Only Con is that it is often out of stock

J
Jessica C.
Quality:
Needs improvement
Excellent quality
Value:
Not a good value
Excellent value
Professional treatments: No
Age: 40 to 60 years old
Gender: Female
Recommends this product: No
Love that it's SPF 50 with no chalky residue

Pros: no chalky finish, no strong smell, easy to blend into the skin, high SPF
Cons: leaves skin a little shiny; my sensitive skin can feel a little tingly/irritated after applying it if I'm well exfoliated. The sensitivity subsides after 5-10 mins so I'll finish using the product but I'm not sure I'll buy it again.

M
Melody M.
Professional treatments: Occasionally
Age: Above 60 years old
Gender: Female
Recommends this product: Yes
This product has proven to be an amazing product for my skin

This product has proven to be an amazing product for my skin. Thank you to those who created the formula. Continue to create! Our skin will be happy!

A
Anonymous
Quality:
Needs improvement
Excellent quality
Value:
Not a good value
Excellent value
Professional treatments: Occasionally
Age: 40 to 60 years old
Gender: Female
Recommends this product: Yes
The best!!!

This is probably my 6th bottle of peptide rich defense SPF 50. There is nothing better!!!

M
M.G.

Love this sunscreen! Only one that has never broken my skin out. Also I love the dewey look it gives my
Skin. It also a wonderful moisturizer

J
Joan Z.
Quality:
Needs improvement
Excellent quality
Value:
Not a good value
Excellent value
Professional treatments: Yes
Age: 40 to 60 years old
Gender: Female
Recommends this product: Yes
Incredible moisturizer and sunscreen

Incredible moisturizer and sunscreen. Great sun block ! My only negative would be the smell of the lotion.

R
Rachelle M.
Quality:
Needs improvement
Excellent quality
Value:
Not a good value
Excellent value
Professional treatments: No
Age: 40 to 60 years old
Gender: Female
Recommends this product: Yes
"The best SPF 50 I’ve tried for sensitive skin!

"The best SPF 50 I’ve tried for sensitive skin! It has a velvety, non-greasy finish that doesn't leave a white cast. It absorbs quickly and works perfectly as a base for makeup—no pilling or heaviness. My face feels protected and nourished all day!"

b
barbara N.
Great thanks very

Great thanks very much

S
Sara C.
Quality:
Needs improvement
Excellent quality
Value:
Not a good value
Excellent value
Professional treatments: Yes
Age: 40 to 60 years old
Gender: Female
Recommends this product: Yes
Love how my face feels moisturized without feeling greasy

Love how my face feels moisturized without feeling greasy.

O
Ok
Quality:
Needs improvement
Excellent quality
Value:
Not a good value
Excellent value
Professional treatments: Yes
Age: 40 to 60 years old
Gender: Female
Recommends this product: Yes
I love

I love it

l
leleca
Great moisturizer with spf

very good product

B
BH
Recommend To a Friend: Yes
age: 25 to 39 years old
Value 1 = Poor Value, 5 = Excellent Value: 4
Quality 1 = low, 5 = high: 5
Game changer

The absolute best. The only product I've been loyal to for years!

m
muddme
look no further

Great product - bonus, has spf!

m
mjjntm
Would highly recommend

I love it

n
nataly
Amazing

Amazing. Love this product.

b
bellag
Great product with SPF

works well and protects

K
Koch
Recommend To a Friend: Yes
age: Above 60 years old
Value 1 = Poor Value, 5 = Excellent Value: 5
Quality 1 = low, 5 = high: 5
SPF 50 Moisturizer

This was just like the original except for the color. I remember that was more beige where this one looks white. It went on smooth and when rubbed in you couldn't see it. There was do whit haze left.

a
azzulf
wonderful!

Love how this feels and protects

k
knazmu
Great!

Would recommend this

C
Courtney
Works well

great moisturizer

B
Betsy G.
Recommend To a Friend: Yes
age: 40 to 60 years old
Value 1 = Poor Value, 5 = Excellent Value: 5
Quality 1 = low, 5 = high: 5
Love the SPF!

I love this product! Been using for years through my esthetician. Due to a recent move I will be ordering online direct now.

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