Serum 16 Rapid Renewal Serum
Serum PM
Rapid Renewal Serum 16 is Cosmedix's Rapid Renewal Serum, thoughtfully formulated for those who want the proven benefits of Retinol without the irritation that typically comes with it.
- Helps improve the appearance of fine lines and wrinkles
- Deeply hydrates, soothes and nourishes a dry complexion
- Helps reduce the look of an uneven skin ton
- Helps improve hydration and prevent moisture loss
- Lightweight, fast-absorbing formula boosts moisture without causing dryness
Rapid Renewal Serum 16 is Cosmedix's Rapid Renewal Serum, thoughtfully formulated for those who want the proven benefits of Retinol without the irritation that typically comes with it.
As a retinoid-dominated formula that offers an exceptional age-defying effect for people with any skin type, this PM serum adds optimal moisture to the skin, in addition to a clinical Retinoid treatment.
The hero ingredient is 16% LG-Retinex, a proprietary Microencapsulated Retinol Complex exclusive to Cosmedix. This encapsulation technology wraps both Retinol and Retinal in a protective delivery system that releases actives gradually onto the skin, reducing the risk of reactivity while maintaining the efficacy that Retinoids are known for.
Since the actives are gradually released, the skin has time to react and absorb. Naturally, there are no cases of high reactivity from applying Serum 16 so far. The microencapsulated formula works gradually to make the skin free from fine lines within weeks.
The bonus: no peeling, redness, or tightness that standard Retinol products so often cause. Serum 16 also packs in Sodium Hyaluronate, which works alongside the Retinoid complex to replenish moisture at the skin's surface, visibly plumping fine lines and softening the complexion's overall texture.
Paired with Squalane, a skin-identical emollient that mimics the skin's own natural oils, the formula maintains moisture levels throughout the night, leaving skin nourished rather than stripped by morning.
Vitamin E (Tocopherol) rounds out the core active complex, providing antioxidant protection against environmental stressors that accelerate visible aging. Its presence in the formula also supports the skin's tolerance of the Retinoid complex, creating a more balanced experience for those who have previously found Retinol too harsh.
The formula is further enriched with Safflower Oleosomes, Glycosaminoglycans, and Sodium Polygamma-Glutamate. All of them are moisture-binding and skin-conditioning agents that reinforce the skin's natural barrier and help lock in the hydration delivered overnight.
In addition, the Honeysuckle Flower Extract adds a calming, antioxidant-rich botanical note that soothes the skin as the actives work.
Cosmedix combines encapsulated retinol and skin calmers to create a unique matrix. But, instead of skin impairments, continuous gentle anti-aging Retinol use here will make your skin smoother, polished, and fresh.
AM - We do not recommend this product for use in the AM, as it may cause skin sensitivity to sun exposure. Protect your results by wearing sunscreen daily.
PM - Apply a small amount to freshly cleansed and toned skin as tolerated every 1-3 nights, working up to nightly use. May be followed with moisturizer if additional hydration is needed.
Q. What is Serum 16 designed to treat?
A. Serum 16 works on fine lines, uneven skin tone, dry, dehydrated skin, and general signs of early aging, all while keeping skin comfortable and hydrated throughout the night.
Q. What is LG-Retinex?
A. LG-Retinex is Cosmedix's own encapsulated blend of Retinol and Retinal. The encapsulation releases the actives gradually, so skin gets the full benefit of Retinol with far less chance of irritation.
Q. Is Serum 16 suitable for sensitive skin?
A. Yes. It was specifically developed for dry, sensitive skin types that don't get along well with traditional Retinol. The encapsulated delivery system and hydrating base make it much gentler than standard Retinol formulas.
Q. Why is Serum 16 a PM-only product?
A. Retinoids react fast when exposed to sunlight (even when you are wearing an SPF). The PM routine is designed for retinol application, and its long-lasting results become visible within a few weeks.
Q. How often should I use Serum 16?
A. Let an aesthetician analyze your skin and recommend the appropriate retinol dosage. On a broader scale, estheticians prescribe using serum 16 for 2 to 3 times a week.
Q. Can I use a moisturizer on top of Serum 16?
A. Retinoids cast a drying effect on the skin, especially the face. The softer, more supple, and more nimble your skin is, the more it absorbs retinoids and perceives their effects.
Q. How is Serum 16 different from other Retinol serums?
A. Serum 16 uses microcapsulated retinol, which most mass-market retinoids don’t use. When the skin is dry or losing moisture, Serum 16 is a default choice. The encapsulated formula also works well on reactive and oversensitized skins.
Q. When will I start seeing results with Serum 16?
A. Retinol works fast. However, assured and sustainable results may take up to 3 weeks. At first, the skin will look sharper and plumper. Gradually, you will see more details, such as a softer skin tone that is more radiant and supple.
Q. Can Serum 16 be used after professional treatments?
A. In professional treatment, Serum 16 is the first choice. If your skin is going through the recovery stage, aestheticians usually recommend pausing retinol treatment. However, encapsulated retinols can still be absorbed by the skin. It is a gentle mechanism and a more practical option for sensitive skin.
Aqua/Water/Eau, Hamamelis Virginiana (Witch Hazel) Water, Carthamus Tinctorius (Safflower) Oleosomes, Glycerin, Phospholipids, Sodium Acrylates Copolymer, Hydrogenated Polyisobutene, Sodium Lactate, Polysorbate 20, Cetyl Alcohol, Retinal, Retinol, Proline (L), Sodium Hyaluronate (L), Helianthus Annuus (Sunflower) Seed Oil, Tapioca Starch, Leuconostoc/Radish Root Ferment Filtrate, Lonicera Caprifolium (Honeysuckle) Flower Extract, Lonicera Japonica (Honeysuckle) Flower Extract, Santalum Austrocaledonicum (Sandalwood) Wood Oil, Lavandula Hybrida (Lavandin) Oil, Galactoarabinan, Glycosaminoglycans, Sodium Polygamma-Glutamate, Tocopherol (D-Alpha), Squalane, Hydroxypropyl Starch Phosphate, Dimethicone, Polyglyceryl-10 Stearate, Gluconic Acid, Xanthan Gum, Tetrasodium Edta, Citric Acid, Alcohol, Potassium Sorbate, Sodium Glycolate, Sodium Hydroxide, Trisodium Edta, Benzoic Acid, Sodium Benzoate, Linalool, Limonene, Coumarin, Geraniol.
Benefits & Usage
Botanical Hero
Honeysuckle (flower)
Honeysuckle is rich in antioxidants and anti-inflammatory properties, helping to soothe irritation, hydrate the skin, and promote a radiant, healthy complexion.
How to Apply
AM - We do not recommend this product for use in the AM, as it may cause skin sensitivity to sun exposure. Protect your results by wearing sunscreen daily.
PM - Apply a small amount to freshly cleansed and toned skin as tolerated every 1-3 nights, working up to nightly use. May be followed with moisturizer if additional hydration is needed.
Transformative Ingredients
Clean. Clinical. Luxurious
Clinically Proven Efficacy
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COSMEDIX proprietary encapsulated blend of Retinol and Retinal that helps reduce the look of lines and medium to deep wrinkles
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Boost hydration and help prevent moisture loss
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Helps protect the skin from environmental stressors
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Works great
Best serum
Amazing product. Love it
Will buy it again
COSMEDIX Serum 16 Rapid Renewal Serum is a standout in my skincare routine. It combines 16% microencapsulated retinol with hydrating ingredients like squalane and sodium hyaluronate, making it effective yet gentle. The serum absorbs quickly, leaving my skin feeling nourished and smooth without any irritation. Over time, I've noticed a more even skin tone and a reduction in fine lines. It's ideal for those seeking age-defying benefits with added hydration.([Crystal Clear Skin Management][1])
[1]: https://crystalclearskin.com.au/products/cosmedix-serum-16?utm_source=chatgpt.com "Cosmedix Serum 16 - Rapid Renewal Serum - Crystal Clear Skin Management"
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