Serum 16

Serum 16
Serum 16
Serum 16
Serum 16
Serum 16
Serum 16
Serum 16
Serum 16

Serum 16


Rapid Renewal Serum

Introduce Retinol Into Your Routine

Serum 16 features hydrators coupled with retinol to target signs of aging while protecting the skin's moisture barrier function. This innovative formula helps reduce the appearance of uneven skin tone, smooth wrinkles and boost moisture without causing redness, dryness or irritation. Serum 16 offers the greatest potency, delivery and stability of LG-Retinex available today.

Real Results
- 90% reported a brighter, more even skin tone
- 88% reported noticeably firmer skin
- 75% reported less apparent wrinkles
*Based on a six-week clinical study.

Transformative Ingredients
Vitamin A| Helps reduce the appearance of fine lines and wrinkles.

  • Benefits
  • Application
  • Ingredients


A combination of science and botanical ingredients help firm skin and smooth lines and wrinkles.

Conditioning moisturizers help attract and retain vital moisture in the skin.

Helps to even skin tone by reducing the look of acne scars, dark spots and hyper-pigmentation.

Free radical-fighting antioxidants defend skin from environmental stress that can cause inflammation and damage to collagen and elastin.

Acne is caused when oil, hair and dead skin cells clog pores. Ingredients such as Salicylic Acid and AGP Complex help stimulate cell turnover to curb breakouts.

Improved texture and proper product absorption is due to exfoliation. When the surface layer of the skin is removed, fresh skin is revealed and can absorb active ingredients easier.

LG-Retinex – a microencapsulated retinol for drier, sensitive skin – encourages skin renewal to reduce the appearance of wrinkles and imperfections.

For those with severe gluten sensitivities or Dermatitis Herpetiformis, rest assured this product is gluten free.



Apply a small amount to freshly cleansed and toned skin as tolerated every 1-3 nights, working up to nightly use. May be followed with moisturizer if additional hydration is needed. Protect your results by wearing sunscreen daily


We do not recommend this product for use in the AM, as it may cause skin sensitivity to sun exposure.


All Ingredients

Aqua, Hamamelis Virginiana (Witch Hazel) Water, Carthamus Tinctorius (Safflower) Seed Oil, Glycerin, Sodium Lactate, Sodium Acrylates Copolymer, Phospholipids, Hydrogenated Polyisobutene, Polysorbate 20, Cetyl Alcohol, Retinol, Retinal, Proline (L), Sodium Hyaluronate (L), Helianthus Annuus (Sunflower) Seed Oil, Tapioca Starch, Leuconostoc/Radish Root Ferment Filtrate, Lonicera Caprifolium (Honeysuckle) Flower Extract, Lonicera Japonica (Honeysuckle) Flower Extract, Santalum Austrocaledonicum (Sandalwood) Wood Oil, Lavandula Hybrid (Lavandin) Oil, Galactoarabinan, Glycosaminoglycans, Potassium Hydrolyzed Polygamma-Glutamate, Tocopherol (D-alpha), Squalane, Hydroxypropyl Starch Phosphate, Dimethicone, Polyglyceryl-10 Stearate, Lecithin, Xanthan Gum, Tetrasodium EDTA, Citric Acid, Alcohol, Potassium Sorbate




Benefit Clean




Serum 16





4.8 / 5.0
35 Reviews
5 Stars
4 Stars
3 Stars
2 Stars
1 Star
Best brand ever
I've tried many brands over the years and believe Cosmedix is by far the best. The serums, in particular, are incredible.
January 20, 2019
3 weeks ago
Great product
I have only used it a few times and have noticed a difference. I cannot wait to see the results after many uses!
January 10, 2019
Post Falls , ID
Age: 25-44
1 month ago
Love Cosmedix
I am loving all the products that I ordered. My skin is softer, brighter, and dark spots are slower going away. I have only been using my products for 2 weeks and love them!
December 23, 2018
1 month ago
Serum 16 Rapid Renewal Serum
Use this product nightly for a great restorative feel in the morning.
This review was collected as part of a promotion
December 9, 2018
Essential for sensitive skin
I really like this serum. It is gentle enough for my sensitive skin and doesn't cause any flare ups or extra redness. I notice when I run out and need to buy more.
This review was collected as part of a promotion
December 6, 2018
Smoothest skin!
I found that using this product nightly has greatly improved skin texture and minimized pores. I have never felt so confident in my skin before!
This review was collected as part of a promotion
November 28, 2018
I am enjoying my much smoother skin since using Serum 16 for only three weeks!
November 18, 2018
2 months ago
Best ever
It really helps keep my skin moisturized and helps with aging
This review was collected as part of a promotion
November 15, 2018
This is the best serum I have ever used. So great! I think my skin looks younger.
November 14, 2018
Aurora, CO
Age: 25-44
2 months ago
Enjoying the serum 16 results
Every morning my face looks refreshed clean after using Serum 16. I have not had any sensitivity to this product and look forward to seeing what changes I see after a few months.
November 8, 2018
3 months ago