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Define Age-Defying Treatment with Hydroxy Acids & Retinol

$90.00
Item is in stockHurry! Low inventoryItem is out of stock Item is unavailable
This multi-tasking Age-Defying Treatment with Hydroxy Acids & Retinol gently exfoliates the skin to promote a smoother-looking texture by helping to reduce the appearance of fine lines, wrinkles and an uneven complexion. Designed to be the first skincare product in your retinol journey, this face cream is formulated with 2% AGP Retinol Complex and Alpha Hydroxy Acids, making it gentle enough for all skin types. The lightweight, skin-loving formula helps reveal the next layer of skin while restoring hydration to the complexion for a more supple, even-looking skin tone.

1.5 oz / 45 g
Build Your Routine
  • Delivers a rush of hydration to the skin
  • Helps reduce the appearance of wrinkles and an uneven skin tone
  • Gently exfoliates the skin to reveal a softer, smoother-looking skin texture
PM Use
Lotion and Cream
Aging and All skin types

Benefits & Usage

Clean. Clinical. Luxurious.

TRANSFORMATIVE INGREDIENTS

Clinically Proven Efficacy.


This retinol treatment delivers impressive results for age-defying care. Customers said it "makes skin feel smooth and hydrated" with visible improvements in texture, tone, and pigmentation. Many report reduced fine lines, clearer pores, and a youthful glow. While gentle for most, some experienced initial dryness or sensitivity. Best used at night with sunscreen during the day.

  • My skin feels so smooth and hydrated, and I love that tingly feeling when I put it on.
  • Within one week, I could tell a drastic improvement in the tone of my skin.
  • The fine lines around my eyes have disappeared. The age spots on my cheeks are gone.
Scars (positive)Wrinkles (positive)Retinol (positive)Acne (positive)Spots (positive)
  • 5 stars: 87 (91%)
  • 4 stars: 9 (9%)
  • 3 stars: 0 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
s
shoegi
Amazing

Amazing. Love this product.

K
KimBarthlow
Recommend To a Friend: Yes
age: Above 60 years old
Value 1 = Poor Value, 5 = Excellent Value: 5
Quality 1 = low, 5 = high: 5
Game Changing!

This product is game changing! After one week, I see a difference! I love Cosmetics!

C
Courtney
Recommend To a Friend: Yes
age: 25 to 39 years old
Value 1 = Poor Value, 5 = Excellent Value: 5
Quality 1 = low, 5 = high: 5
Wonderful

This has helped my face when nothing else couldn't!

G
Georgia
Recommend To a Friend: Yes
age: 25 to 39 years old
Value 1 = Poor Value, 5 = Excellent Value: 5
Quality 1 = low, 5 = high: 5
Great product for clear bright skin

This is my second buy of this product and it helps with my dark spots , not too harsh on the skin but really does the job like an intense peel , highly recommend for bright skin the next morning and for pigmentation

h
hilli@
Amazing Product!

Amazing product.

j
jessic
Amazing

Wonderful product! Love the way my skin feels after

A
Anonymous
Great purchase!

Very impressed with this product-my skin was immediately more balanced and texture was just. I have very very sensitive skin and this product worked well. Would definately buy again!

A
Anonymous
Great purchase!

Very impressed with this product-my skin was immediately more balanced and texture was just. I have very very sensitive skin and this product worked well. Would definately buy again!

J
Jenna R.
Love it

Tightens and tones. Improves texture. Just make sure to apply at night and use sunscreen during the day!

A
Anonymous
Love this product

This product makes my skin very smooth and soft. I will contine to buy it even though it is a little pricy.

A
Anonymous
Love this product

This product makes my skin very smooth and soft. I will contine to buy it even though it is a little pricy.

K
Karen Y.
Game changing product

This product is awesome. I use it with Simply Brilliant and it made a difference in my pigment issues and the tone of my skin and neck. I love these products and will be adding more to my regimen.

A
Anonymous
This product has been a ...

This product has been a life changer! I suffer from adult acne and it has gotten worse over the years until I started using Cosmedix, especially the Define. My skin looks smoother and softer. My acne scars are also starting to disappear. It also lasts a long time since a little goes a long way.

A
Anonymous
This product has been a ...

This product has been a life changer! I suffer from adult acne and it has gotten worse over the years until I started using Cosmedix, especially the Define. My skin looks smoother and softer. My acne scars are also starting to disappear. It also lasts a long time since a little goes a long way.

C
Ceylan D.
This made a huge difference

This made a huge difference in my skin tone and overall texture!

A
Anonymous
My Secret Weapon!

This has now been added to my skin care routine. This product feels great to the touch and leaves my face and neck feeling moisturized and soft.

A
Anonymous
My Secret Weapon!

This has now been added to my skin care routine. This product feels great to the touch and leaves my face and neck feeling moisturized and soft.

M
Michelle R.
Appears to work well

Still a little early after purchasing to determine full results but so far my skin appears smoother, with fewer pigmentation patches.

A
Anonymous
Define

Started using cosmedix after a spa visit. I love all of the products but definitely saw a big difference after using Define for a couple of weeks. It is now part of my routine 3 or 4 times a week. I love when people tell me how great my skin looks.

A
Anonymous
Define

Started using cosmedix after a spa visit. I love all of the products but definitely saw a big difference after using Define for a couple of weeks. It is now part of my routine 3 or 4 times a week. I love when people tell me how great my skin looks.

H
Heather S.
So gentle and nice

So far this retinol has been amazing for my sensitive and acne prone skin. I've used several others.. with extreme dryness and redness. My face doesn't feel tight and raw in the morning. I can use it three times a week versus with others only once a week. I do get very small one or two acne bumps. That's normal for my skin. Even though this is gentle, I would definitely still use your sunscreen. Or don't go in the direct sun after using it. So far everything from this website has been a godsend for my poor sad skin.

a
alina
Alina

omg amazing product !!!!!!

C
Carol R.
Nice product, feels great.

Nice product, feels great.

A
Amy S.
50 really is the new 40 with define!

My skin has never looked or felt better! I use Define every other day to avoid over drying and it works like a dream!

B
Barbara B.
My order arrived safe +

My order arrived safe + sound....and my face is happy to have a new tube of Cosmedix to use....thanks for a great product !!!

B
Bianca B.
My favorite and now ONLY

My favorite and now ONLY face cream! Highly recommend

S
Sylza E.
Love, love, love this cream!

Love, love, love this cream! I've been using it for over a year consistently and I feel like my skin is smoother, less bumpy, my dark spots are significantly lighter. I really wish I would have taken before pictures. But I can't say enough good things about this product.

A
Anonymous
define

Love this product. I use in in conjunction with my refine

A
Anonymous
define

Love this product. I use in in conjunction with my refine

D
Deborah N.
Love this product! Smooths and

Love this product! Smooths and evens my skin with no irritation. I'm 57 and I've used this product for years and credit it with keeping my skin youthful looking.

C
Cathy W.
Love Define. My skin looks

Love Define. My skin looks absolutely glowing and youthful when I use define. It's hard to explain, but my face, neck, and declotte look so much younger than my actual age off 69. I've used Cosmedix products off and on for 10+ years and when I'm "on" with Cosmedix, I see a lovely difference. Cosmedix is now my skin care of choice. My older friends are envious of my beautiful skin. I recommend Cosmedix.

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