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Microbiome Renewal Complexion Set

$85.00

The perfect introduction to COSMEDIX. Two professional daily essentials that gently exfoliate, replenish hydration, and help support a healthy-looking skin barrier and balanced microbiome.

Purity Clean: 5 FL OZ / 150 mL
Harmonize: NET WT 1.87 OZ / 53 g

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✓ Gently exfoliates with L-Lactic Acid to help smooth texture and reveal brighter-looking skin
✓ Helps support a balanced skin microbiome for a healthier-looking complexion
✓ Replenishes hydration with adaptogenic botanicals and Snow Mushroom
✓ Supports a stronger-looking skin barrier with postbiotic-derived ingredients
✓ Two everyday essentials expertly paired for a simple, effective professional routine

Microbiome Renewal is a limited-edition holiday set featuring Purity Clean and Harmonize, two of COSMEDIX's most trusted daily essentials expertly paired to gently exfoliate, replenish hydration, and help support a healthy-looking skin barrier. Designed as the perfect introduction to professional skincare, this duo delivers a complete complexion ritual at an accessible entry price.

Purity Clean is an exfoliating cleanser formulated with 5% L-Lactic Acid to gently resurface rough, uneven texture while removing impurities. Unlike harsh scrubs that can compromise the skin barrier, this AHA-based formula dissolves dead surface cells to help reveal smoother, brighter-looking skin. It's the bestselling cleanser in the COSMEDIX line, trusted by aestheticians as a daily treatment cleanser that exfoliates and cleanses in one step.

Harmonize is a microbiome-supporting moisturizer formulated with Lactobacillus Ferment Lysate Filtrate (a postbiotic-derived ingredient), Tremella Fuciformis (Snow Mushroom), and a blend of adaptogenic botanicals including Reishi, Chaga, and Ashwagandha. This formula helps support the skin's natural microbiome balance while delivering deep, lasting hydration through Squalane and Mango Seed Butter. The result is skin that looks calmer, more balanced, and better equipped to maintain its own moisture.

Together, these two formulas create a daily ritual that addresses the fundamentals: Purity Clean resurfaces and renews, and Harmonize restores and protects. The pairing works because gentle exfoliation helps optimize how skin receives hydration, while microbiome-supporting care helps maintain the results of that renewal.

This set reflects COSMEDIX's core philosophy that professional skincare should be simple, effective, and approachable. Aestheticians recommend this exact pairing for clients beginning their professional skincare journey or anyone seeking a streamlined routine that covers cleansing, exfoliation, hydration, and barrier support in just two steps.

At $85 (a $113 value), Microbiome Renewal offers 25% savings on two professional favorites. Limited edition. Available only this holiday season.

  1. What is the Microbiome Renewal set?
    A: Microbiome Renewal is a limited-edition holiday set pairing Purity Clean (an exfoliating cleanser with 5% L-Lactic Acid) with Harmonize (a microbiome-supporting moisturizer with postbiotic-derived Lactobacillus and adaptogenic botanicals). Together they form a complete daily cleansing and hydration ritual.
  2. Who is Microbiome Renewal best for?
    A. Anyone looking for a simple, effective professional skincare routine. It's especially ideal for those new to COSMEDIX or professional-grade skincare, those with rough or uneven texture, anyone concerned with skin barrier health, or gift-givers who want a thoughtful introduction to clinical skincare.
  3. What does "microbiome care" mean in skincare?A. Your skin's microbiome is the community of beneficial microorganisms that live on its surface and help maintain barrier health. Harmonize contains Lactobacillus Ferment Lysate Filtrate (a postbiotic-derived ingredient) that helps support this natural ecosystem, promoting skin that looks calmer, more balanced, and better hydrated.
  4. Does Purity Clean contain AHA? Will it irritate my skin?
    A. Yes, Purity Clean contains 5% L-Lactic Acid, a gentle AHA. It's formulated to be mild enough for twice-daily use without stripping or irritating skin. Lactic Acid is one of the gentlest AHAs because it also has hydrating properties. However, always follow with sunscreen in the morning since AHAs can increase sun sensitivity.
  5. Can I use Purity Clean if I have sensitive skin?
    A. Purity Clean is generally well-tolerated, but if you have a very reactive or compromised barrier, Elite Gentle Clean (in the Elite Balance set) may be a better starting cleanser. Purity Clean's L-Lactic Acid provides gentle exfoliation that most skin types handle well with daily use.
  6. What are adaptogens in skincare?
    A. Adaptogens are botanical ingredients traditionally used to help the body manage stress. In Harmonize, adaptogenic extracts like Reishi Mushroom, Chaga, Ashwagandha, and Rhodiola help support the appearance of calmer, more resilient-looking skin and support the skin's natural ability to maintain hydration and balance.
  7. How is Harmonize different from a regular moisturizer?
    A. Harmonize goes beyond surface hydration. Its postbiotic-derived Lactobacillus and Snow Mushroom (Tremella Fuciformis) work to help support the skin's natural microbiome and moisture barrier, meaning skin becomes better at maintaining its own hydration over time rather than just feeling moisturized temporarily.
  8. Can I add serums between these two steps?
    A. Absolutely. After cleansing with Purity Clean, apply any treatment serums (brightening, anti-aging, hydrating) and then follow with Harmonize as your final moisturizing step. This duo is designed as a foundation that pairs well with any COSMEDIX serum.
  9. Why do aestheticians recommend this pairing?
    A. Aestheticians trust Purity Clean because it's a two-in-one exfoliant and cleanser that's gentle enough for daily use. Paired with Harmonize, it creates a complete routine that covers cleansing, exfoliation, hydration, and barrier support in just two steps, making it the ideal starter ritual for new professional skincare clients.
  10. Is this set available year-round?
    A. No. Microbiome Renewal is a limited-edition holiday exclusive at this special pricing ($113 value for $85). Both Purity Clean and Harmonize are available individually year-round at full retail, but the 25% savings is only available this season.
AM/PM Use
Cream and Gel
All skin types

Clean. Clinical. Luxurious.

TRANSFORMATIVE INGREDIENTS

Lactobacillus Ferment Lysate Filtrate
L-Lactic Acid (5%)
Tremella Fuciformis (Snow Mushroom)

Benefits & Usage


Microbiome Renewal Complexion Set

CLEAN & CLINICAL, BACKED BY SCIENCE

Botanical ingredients meet clinical-grade actives for proven results.

  • 5 stars: 142 (93%)
  • 4 stars: 8 (5%)
  • 3 stars: 2 (1%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
This product has no reviews of its own. The merchant grouped it with related products, so the reviews shown are from across that group.
M
Marilyn B.
Professional treatments: Yes
Age: Above 60 years old
Gender: Female
Recommends this product: Yes
F
Farah F.
Quality:
Needs improvement
Excellent quality
Value:
Not a good value
Excellent value
Professional treatments: Yes
Age: 25 to 39 years old
Gender: Female
Recommends this product: Yes
Smells Amazing

The benefits are one thing, but the smell of an effective product always is a good feeling!

A
Alcione G.
Quality:
Needs improvement
Excellent quality
Value:
Not a good value
Excellent value
Professional treatments: Yes
Age: 25 to 39 years old
Gender: Female
Recommends this product: Yes
I love it. It’s my go to

Lightweight but moisturizing

A
Anonymous
Value:
Not a good value
Excellent value
Professional treatments: Occasionally
Age: Above 60 years old
Gender: Female
Recommends this product: Yes
Great moisturizer!

Harmonize moisturizer is wonderful. It’s a light cream that I use at nighttime.

m
martin
Love this moisturizer

You must try this

V
Vivian77
Recommend To a Friend: Yes
age: 25 to 39 years old
Value 1 = Poor Value, 5 = Excellent Value: 5
Quality 1 = low, 5 = high: 5
Harmonize your Skin!

I recently received Cosmedix's Harmonize Microbiome Boosting Moisturizer, I love the sleek air tight packaging to make sure the product stays fresh. As well as their signature metallic accents featured in a silver rounded bottle with a luxe white cream inside. The moisturizer itself feels lightweight on the skin while still delivering hydration and soothing irritation and any redness I have on my face. The moisturizer leaves my skin feel light, bouncy, and refreshed without weighing me down or feeling tacky/greasy. I use this moisturizer nightly and have noticed and overall improvement in my skin retaining moisture throughout the night as well as the texture of my skin being very soft and smooth. The overall complexion of my skin has improved looking brighter and more radiant. The product is packed with rich ingredients to help truly heal and nourish your skin. This product as it's versatile and can be used on all skin types as well as day and night use. Overall, a great product and I would recommend to anyone looking for a solid and reliable moisturizer to their routine!
*this product was provided for promotional purposes in exchange for my honest review*

G
Ggreen
Recommend To a Friend: Yes
age: 40 to 60 years old
Wonderful

Love everything about this product! It goes on light and airy and the smell reminds me of the spa. I use this daily!

K
KimBarthlow
Amazing

Amazing. Love this product.

b
bellag
Great product

I would recommend this

K
Kate S.
Recommend To a Friend: Yes
age: 25 to 39 years old
Value 1 = Poor Value, 5 = Excellent Value: 5
Quality 1 = low, 5 = high: 5
Great Moisturizer

Love this product! It's so light and works well with make up!

o
olenka
Look no further

This is by far the best moisturizers

M
Monica
Recommend To a Friend: No
age: 40 to 60 years old
Value 1 = Poor Value, 5 = Excellent Value: 4
Quality 1 = low, 5 = high: 5
Perfect

My daughter, who has very sensitive skin and is sensitive to the feel of anything on her face loves this product. It is perfectly formulated to moisturize young skin while not leaving any kind of oily feel.

0
0000ph
Amazing

Amazing product. Love it.

o
onlyvl
Great moisturizer

Works well

s
saselv
One of the best

Highly recommended

A
Apaige23
Recommend To a Friend: Yes
age: 25 to 39 years old
Value 1 = Poor Value, 5 = Excellent Value: 5
Quality 1 = low, 5 = high: 5
The perfect moisturizer!

My favorite moisturizer since discovering it! Harmonize is everything I've ever wanted in a moisturizer for my skin. For reference I'm a 27 year old Caucasian woman from the Midwest with combination skin that leans dry. This moisturizer leaves my skin looking plump, smooth, firm, clear, and rejuvenated. It's formulated with vitis vinifera, zingiber officinale, and Boswellia serrata which is an age defying cocktail of fruit and plant extracts that help support skin's natural microbiome while protecting it from external environmental stressors. Its other star ingredients are Bisabolol (L-alpha) which helps sooth and smooth skin along with Lactococcus Ferment Lysate which is a nourishing probiotic that supports and improves your skin's microbiome and barrier function. Altogether they give my skin exactly what it needs in a moisturizer. Highly recommend! I received this product as part of an educational promotion event and will continue to repurchase it.

J
Jghazala
Recommend To a Friend: Yes
age: 25 to 39 years old
Value 1 = Poor Value, 5 = Excellent Value: 5
Quality 1 = low, 5 = high: 5
Harmonize Microbiome Boosting Moisturizer

I've been using the Harmonize Microbiome Boosting Moisturizer for a few weeks now, and I'm genuinely impressed. The texture is lightweight but still deeply hydrating, and it absorbs beautifully without leaving any greasy residue. What I really love is how calming and balancing it feels my skin tends to get irritated or uneven, but since using this, it's felt noticeably more stable and healthy.

The formula is gentle and clean, which I appreciate, especially knowing it's focused on supporting the skin's natural microbiome. It pairs really well with other products in my routine too no pilling or weird reactions.

If you're looking for a moisturizer that feels both effective and soothing, especially if your skin is stressed or unbalanced, this one is definitely worth trying!

D
Dkings
Recommend To a Friend: Yes
age: 25 to 39 years old
Value 1 = Poor Value, 5 = Excellent Value: 5
Quality 1 = low, 5 = high: 5
Love it

Cosmedix Harmonize has a lightweight, silky texture that glides smoothly onto the skin. It absorbs quickly, leaving no greasy residue behind, which I appreciate. I typically apply it after cleansing, and it feels incredibly refreshing. A little goes a long way, so just a few drops are enough to cover my face and neck.After using Harmonize consistently for a few weeks. My skin feels more balanced and less reactive to environmental stressors. It has also helped to improve my overall complexion, leaving my skin looking healthier and more radiant. I've even noticed that my makeup applies more smoothly over it. It delivers on its promises of soothing and balancing, and I love how it enhances my skincare routine. It is gentle yet effective moisturizer that promotes calmness and hydration,

A
Alyssam2626
Recommend To a Friend: Yes
age: 25 to 39 years old
Value 1 = Poor Value, 5 = Excellent Value: 5
Quality 1 = low, 5 = high: 5
Silky soft skin!

A really silky soft and gentle moisturizer that's made my skin hydrated and bouncy without causing irritations or breakouts! It has a scent that's very fresh and clean almost like hotel soap and it quickly absorbs into my skin without leaving it feeling sticky or greasy! I love the applicator too!

K
Kyubino12
Recommend To a Friend: Yes
age: 25 to 39 years old
Value 1 = Poor Value, 5 = Excellent Value: 5
Quality 1 = low, 5 = high: 5
Amazing moisturizer

The Harmonize Microbiome Boosting Moisturizer works amazingly on my skin! This moisturizer is exactly what I need, especially during the summertime when my skin tends to get dry and uncomfortable. Normally, heat and sun exposure leave my face feeling tight and dehydrated, but this product has completely changed that. From the very first use, I noticed a difference - my skin felt soothed, more balanced, and deeply hydrated. It has a light, breathable texture that absorbs quickly without feeling greasy, which I really appreciate in warm weather. I also love that it supports my skin's natural microbiome, helping it stay healthy and strong even in challenging conditions. Since adding it to my routine, my skin looks smoother, feels softer, and stays moisturized all day. It truly brings comfort back to my skin. I'm so glad I found this product - it's definitely a summer skincare essential for me.

S
Sreya
Recommend To a Friend: Yes
age: 25 to 39 years old
Quality 1 = low, 5 = high: 5
Soothing and hydrating

COSMEDIX Harmonize Microbiome Boosting Moisturizer is my new favorite addition to my skincare routine. This is my first time experience with this brand and I was very excited about it. I love the nice bottle. I use it daily in the morning and night and love the texture on my skin. It is light weight , absorbs easily into skin without leaving any residue and very hydrating. A little amount is enough for the whole face. After consistently using this moisturiser i have noticed improvement in dryness, dullness, and uneven skin tone .This moisturiser calms and soothes my skin and strengthens the skin barrier. I have applied makeups over this moisturiser and it sits very well. I love the pump dispenser which makes it easier to pull out the desired amount of moisturiser. This product was provided for promotional purposes in exchange for my honest review

K
Koko
Recommend To a Friend: Yes
age: 25 to 39 years old
Value 1 = Poor Value, 5 = Excellent Value: 4
Quality 1 = low, 5 = high: 5
Very hydrating and soothing

I am oily and very acne prone and tend to break out occasionally. I have PIH. To help reduce it, I have been exfoliating and using actives, so I actively seek out products for skin repair.
I love the packing. It had a capsule like shape that was futuristic. It also had an interesting way that it pumped out; it comes out from the top, and you then scoop it out with your finger. It had a creamy appearance. A little goes a long way. The first time I tried it, I did two pumps but then realized I only needed one. Despite its creamy appearance, it was very lightweight, and hydrating. It was not greasy. The smell is very mild. I used this product in conjunction with the benefit balance and clarity serum, and it helped to moisturize, calm, and soothe my skin.

This product was provided for promotional purposes in exchange for my honest review

Y
Yenic
Recommend To a Friend: Yes
age: 18 to 24 years old
Value 1 = Poor Value, 5 = Excellent Value: 5
Quality 1 = low, 5 = high: 5
Lightweight and nourishing

This moisturizer feels like comfort in a jar. It's breathable and lightweight, yet deeply hydrating. It sinks in fast without leaving a greasy residue, making it perfect for both morning and night. My skin has felt calmer, less reactive, and more consistently hydrated since I started using it. Plus, it pairs beautifully with the rest of the Cosmedix line.

Disclaimer: This product was provided for promotional purposes in exchange for my honest review.

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